勠力同心为化学与精细化工广东省实验室提供皮秒双波长光纤激光源

2023-3-1 22:55:45

Picosecond dual-wavelength fiber-based laser source for Guangzhou CCELAB

勠力同心为化学与精细化工广东省实验室提供皮秒双波长光纤激光源

It took a lot of heart and sweat, but now it's done: WinWinTec International Group and TRUMPF Group Active Fiber Systems have won a bidding competition from a southern China research group to develop a dual-wavelength picosecond fiber laser for Stimulated Raman Scattering (SRS) microscopy.

经过不懈地努力与沟通，在与德国WinWinTec 国际集团和德国通快(TRUMPF)集团Active Fiber Systems协作下，我们赢得了华南地区这个关于开发具有两种波长的用于受激拉曼散射的皮秒光纤激光器(SRS)显微镜的研究小组的竞标。

With the SRS laser, we address a tun ability rangefrom 1000 to 3300 cm-1with a spectral bandwidth of <10cm-1 (output 1) and <15cm-1 (output 2), respectively. For our users, which are researchers from the Zhongshan School of Medicine, Sun-Yat-Sen University, and the Chemistry and Chemical Engineering Guangdong Laboratory, we will integrate it into a general-purpose SRS microscope to achieve rapid chemical mapping in biological materials and pharmaceuticals. Furthermore, the SRS laser will be used for developing SRS tags for medical diagnosis.

使用Active Fiber Systems研发的 SRS 激光器，我们能够提供在光谱带宽<10cm-1（输出 1）或<15cm-1（输出 2）从 1000 至3300 cm-1 的可调谐范围。我们的用户由中山大学中山医学院和化学与精细化工广东省实验室的研究人员组成，未来会把我们提供的SRS激光器集成到通用 SRS 显微镜中，以实现对生物材料进行快速化学映射及用于制药。此外，SRS 激光还被用于医疗诊断的SRS标签的开发。

Our SRS lasers involve third-order nonlinear optical processes where three electromagnetic waves interact with the sample volume to generate a characteristic optical signal. Upon coincidence of the difference frequency of a pair of such waves corresponding to the frequency of a Raman resonance, the signal is greatly enhanced. These techniques are typically employed to image bio-molecules in living or fixed cells or tissues. They offer the great advantage to not require any sort of labeling or staining. Additionally, spectral information is obtained using broadband light sources. The signal-to-noise ratio of these applications benefits greatly from the application of pulsed lasers at high repetition rates.

我们的 SRS 激光器采用三阶非线性光学过程，其中三个电磁波与样品体积相互作用并产生特征光信号。在对应于拉曼共振频率的一对这样的波的差频重合时，信号被大大增强。这些技术通常用于对活细胞或固定细胞或组织中的生物分子成像。它们具有无需标记或染色的巨大优势。此外，光谱信息是在宽带光源的帮助下获得的。这些应用的信噪比极大地受益于高重复率脉冲激光的应用。

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